This idea is just out of curiosity. It would be appreciated if you vote your opinion.
Choice 1: The majority of the pups are taken into different households; some might stay with Ryder but no longer do missions. Everyone still likes each other.
Choice 3: Fighting amongst the pups or between the pups and Ryder; causing them to disband. Death of one pup and the others don't want to continue. Natural disaster destroys the Lookout. Etcetera.